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POLR2H

Protein-coding gene in the species Homo sapiens

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Source updated July 17, 2025

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DNA-directed RNA polymerases I, II, and III subunit RPABC3 is a protein that in humans is encoded by the POLR2H gene.

This gene encodes one of the essential subunits of RNA polymerase II that is shared by the other two eukaryotic DNA-directed RNA polymerases, I and III.

01Interactions

POLR2H has been shown to interact with POLR2C, POLR2G, POLR2A, POLR2B and POLR2E.

Watch videos about POLR2HExplainers and documentaries on YouTube (opens in a new tab)

Sources and credits

This article is adapted from the Wikipedia article “POLR2H”, written by its contributors and licensed under CC BY-SA 4.0. Fathomly has changed the layout, removed citation markers, navigation and maintenance notices, and adjusted punctuation. This adapted version is shared under the same license. For references, see the original article.

Images, from Wikimedia Commons:

Protein POLR2H PDB 2f3i.png by Emw, CC BY-SA 3.0

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