Polysorbate
Class of chemical compounds
Polysorbates are a class of emulsifiers used in some pharmaceuticals and food preparation. They are commonly used in oral and topical pharmaceutical dosage forms. They are also often used in cosmetics to solubilize essential oils into water-based products. Polysorbates are oily liquids derived from ethoxylated sorbitan (a derivative of sorbitol) esterified with fatty acids. Common brand names for polysorbates include Lumisorb , Hedjuvan, Kolliphor, Scattics, Alkest, Canarcel, Tween, and Kotilen.
01Examples
- Polysorbate 20 (polyoxyethylene (20) sorbitan monolaurate)
- Polysorbate 40 (polyoxyethylene (20) sorbitan monopalmitate)
- Polysorbate 60 (polyoxyethylene (20) sorbitan monostearate)
- Polysorbate 80 (polyoxyethylene (20) sorbitan monooleate)
The number following the 'polysorbate' part is related to the type of major fatty acid associated with the molecule. Monolaurate is indicated by 20, monopalmitate is indicated by 40, monostearate by 60, and monooleate by 80. The number 20 following the 'polyoxyethylene' part refers to the total number of oxyethylene (-CH2CH2O-) groups found in the molecule.
Sources and credits
This article is adapted from the Wikipedia article “Polysorbate”, written by its contributors and licensed under CC BY-SA 4.0. Fathomly has changed the layout, removed citation markers, navigation and maintenance notices, and adjusted punctuation. This adapted version is shared under the same license. For references, see the original article.
Images, from Wikimedia Commons:
- Polysorbate 60.png by Edgar181, Public domain
Fathomly is not affiliated with or endorsed by the Wikimedia Foundation. Spotted a problem? Tell us.
