TESK1
Protein-coding gene in the species Homo sapiens
Dual specificity testis-specific protein kinase 1 is an enzyme that in humans is encoded by the TESK1 gene.
01Function
This gene product is a serine/threonine protein kinase that contains an N-terminal protein kinase domain and a C-terminal proline-rich domain. Its protein kinase domain is most closely related to those of the LIM motif-containing protein kinases (LIMKs). The encoded protein can phosphorylate myelin basic protein and histone in vitro. The testicular germ cell-specific expression and developmental pattern of expression of the mouse gene suggests that this gene plays an important role at and after the meiotic phase of spermatogenesis.
02Interactions
Sources and credits
This article is adapted from the Wikipedia article “TESK1”, written by its contributors and licensed under CC BY-SA 4.0. Fathomly has changed the layout, removed citation markers, navigation and maintenance notices, and adjusted punctuation. This adapted version is shared under the same license. For references, see the original article.
Images, from Wikimedia Commons:
- Ideogram house mouse chromosome 4.svg by National Center for Biotechnology Information, U.S. National Library of Medicine, Public domain
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