Superkiller complex protein 8
Protein found in humans
Superkiller complex protein 8 (or Ski8) is a protein that in humans is encoded by the SKIC8 gene (previously WDR61). As its name suggests, this protein is part of the superkiller complex, which is involved in extracting mRNA from ribosomes and sending it to the exosome complex to be broken down. Unlike the other Ski complex members, Ski2 and Ski3, in humans (but not yeast) Ski8 is also part of a second RNA-associated protein complex: the PAF1 complex, which is involved in regulating DNA to RNA transcription by RNA polymerase II.
Sources and credits
This article is adapted from the Wikipedia article “Superkiller complex protein 8”, written by its contributors and licensed under CC BY-SA 4.0. Fathomly has changed the layout, removed citation markers, navigation and maintenance notices, and adjusted punctuation. This adapted version is shared under the same license. For references, see the original article.
Images, from Wikimedia Commons:
- Ideogram human chromosome 15.svg by National Center for Biotechnology Information, U.S. National Library of Medicine, Public domain
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