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Setidegrasib

Pharmaceutical compound

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Setidegrasib is an investigational new drug that is being evaluated by Astellas Pharma for the treatment of solid tumors. It is an PROTACs degrader of the KRAS protein harboring a G12D mutation.

01Clinical trials

Setidegrasib in combination with either FOLFIRINOX or NALIRIFOX chemotherapy is currently in phase 3 clinical trials for the treatment of pancreatic cancer.

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This article is adapted from the Wikipedia article Setidegrasib, written by its contributors and licensed under CC BY-SA 4.0. Fathomly has changed the layout, removed citation markers, navigation and maintenance notices, and adjusted punctuation. This adapted version is shared under the same license. For references, see the original article.

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