STEAP3
Protein-coding gene in the species Homo sapiens
Metalloreductase STEAP3 is an enzyme that in humans is encoded by the STEAP3 gene.
STEAP3 is a metalloreductase, capable of converting iron from an insoluble ferric (Fe3+) to a soluble ferrous (Fe2+) form.
STEAP3 and other STEAP protein, with the exception of STEAP1, are predicted to contain a Di-nucleotide binding domain (Rossmann Fold). This has been shown using X-ray crystallography in the cases of STEAP3 and STEAP4 (PDB: 2VNS, 2VQ3 and 2YJZ).
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Sources and credits
This article is adapted from the Wikipedia article “STEAP3”, written by its contributors and licensed under CC BY-SA 4.0. Fathomly has changed the layout, removed citation markers, navigation and maintenance notices, and adjusted punctuation. This adapted version is shared under the same license. For references, see the original article.
Images, from Wikimedia Commons:
- Protein STEAP3 PDB 2VNS.png by Pleiotrope, Public domain
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