SSX2IP
Protein-coding gene in the species Homo sapiens
Afadin- and alpha-actinin-binding protein is a protein that in humans is encoded by the SSX2IP gene. It has been shown that it functions together with WDR8 in centrosome maturation, ensuring proper spindle length and orientation. The SSX2IP-WDR8 complex additionally promotes ciliary vesicle docking during ciliogenesis.
01Interactions
SSX2IP has been initially described as a protein to interact with MLLT4 and Actinin, alpha 1. In the context of centrosome maturation and ciliogenesis it has been shown to interact with WDR8.
Sources and credits
This article is adapted from the Wikipedia article “SSX2IP”, written by its contributors and licensed under CC BY-SA 4.0. Fathomly has changed the layout, removed citation markers, navigation and maintenance notices, and adjusted punctuation. This adapted version is shared under the same license. For references, see the original article.
Images, from Wikimedia Commons:
- Ideogram human chromosome 1.svg by National Center for Biotechnology Information, U.S. National Library of Medicine, Public domain
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