Reference articles on history, science, culture and more
Encyclopedia

60S ribosomal protein L12

Protein found in humans

Image credit is listed at the end of this article.

60S ribosomal protein L12 is a protein that in humans is encoded by the RPL12 gene.

01Function

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L11P family of ribosomal proteins. It is located in the cytoplasm. The protein binds directly to the 26S rRNA. This gene is co-transcribed with the U65 snoRNA, which is located in its fourth intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

02Interactions

RPL12 has been shown to interact with CDC5L.

Watch videos about 60S ribosomal protein L12Explainers and documentaries on YouTube (opens in a new tab)

Sources and credits

This article is adapted from the Wikipedia article 60S ribosomal protein L12, written by its contributors and licensed under CC BY-SA 4.0. Fathomly has changed the layout, removed citation markers, navigation and maintenance notices, and adjusted punctuation. This adapted version is shared under the same license. For references, see the original article.

Images, from Wikimedia Commons:

Fathomly is not affiliated with or endorsed by the Wikimedia Foundation. Spotted a problem? Tell us.