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Pregnane

Chemical compound

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Pregnane, also known as 17β-ethylandrostane or as 10β,13β-dimethyl-17β-ethylgonane, is a C21 steroid and, indirectly, a parent of progesterone. It is a parent hydrocarbon for two series of steroids stemming from 5α-pregnane (originally allopregnane) and 5β-pregnane (17β-ethyletiocholane). It has a gonane core.

5β-Pregnane is the parent of pregnanediones, pregnanolones, and pregnanediols, and is found largely in urine as a metabolic product of 5β-pregnane compounds.

01Pregnanes

Pregnanes are steroid derivatives with carbons present at positions 1 through 21.

Most biologically significant pregnane derivatives fall into one of two groups: pregnenes and pregnadienes. Another class is pregnatrienes.

Steroid nomenclature: Pregnanes have carbons 1 through 21.
Steroid nomenclature: Pregnanes have carbons 1 through 21.

02Pregnenes

Pregnenes have a double bond. Examples include:

Cortisone
Cortisone

03Pregnadienes

Pregnadienes have two double bonds. Examples include:

Cyproterone acetate
Cyproterone acetate
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Sources and credits

This article is adapted from the Wikipedia article Pregnane, written by its contributors and licensed under CC BY-SA 4.0. Fathomly has changed the layout, removed citation markers, navigation and maintenance notices, and adjusted punctuation. This adapted version is shared under the same license. For references, see the original article.

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