Reference articles on history, science, culture and more
Encyclopedia

Phlegmon

Medical condition

A phlegmon is a localized area of acute inflammation of the soft tissues. It is a descriptive term which may be used for inflammation related to a bacterial infection or non-infectious causes (e.g. pancreatitis). Most commonly, it is used in contradistinction to a "walled-off" pus-filled collection (abscess). A phlegmon is inherently dangerous due to its diffuse, uncontained nature; if left untreated, it may either be successfully localized by the immune system to form an abscess, or it may rapidly spread and lead to extensive tissue destruction (necrosis), gangrene, and life-threatening systemic infection (sepsis). A phlegmon can localize anywhere in the body. The Latin term phlegmōn is from Ancient Greek φλέγω (phlégō) 'burn'.

01Signs and symptoms

As with any form of inflammation, phlegmon presents with inflammatory signs dolor (localized pain), calor (increase local tissue temperature), rubor (skin redness/hyperemia), tumor (either clear or non-clear bordered tissue swelling), functio laesa (diminish affected function). There may be systemic signs of infection, such as fever, general fatigue, chills, sweating, headache, loss of appetite.

02Cause

Commonly caused by bacterial infection, as in the case of cellulitis or diverticulitis. Non-infectious causes of phlegmon include acute pancreatitis, where inflammation is caused by leaking of pancreatic digestive enzymes into the surrounding tissues.

Factors affecting the development of phlegmon are virulence of bacteria and immunity strength.

03Diagnosis

In modern medicine, phlegmon is mostly used descriptively in the fields of surgery/surgical pathology and medical imaging. The ultrasound and CT imaging findings of phlegmon are those of focal tissue edema, with no loculated fluid collection to suggest the formation of an abscess.

04Treatment

Since phlegmon describes an area of inflammation, and not a specific disease process, the treatment depends on the cause and severity of the inflammation. Bacterial infections such as cellulitis may be treated by antibiotic therapy, depending on the severity.

Watch videos about PhlegmonExplainers and documentaries on YouTube (opens in a new tab)

Sources and credits

This article is adapted from the Wikipedia article Phlegmon, written by its contributors and licensed under CC BY-SA 4.0. Fathomly has changed the layout, removed citation markers, navigation and maintenance notices, and adjusted punctuation. This adapted version is shared under the same license. For references, see the original article.

Fathomly is not affiliated with or endorsed by the Wikimedia Foundation. Spotted a problem? Tell us.