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POLR2L

Protein-coding gene in the species Homo sapiens

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DNA-directed RNA polymerases I, II, and III subunit RPABC5 is a protein that in humans is encoded by the POLR2L gene.

01Function

This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains four conserved cysteines characteristic of an atypical zinc-binding domain. Like its counterpart in yeast, this unit may be shared by the other two DNA-directed RNA polymerases.

02Interactions

POLR2L has been shown to interact with POLR2C, POLR2A, POLR2B and POLR2E.

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Sources and credits

This article is adapted from the Wikipedia article POLR2L, written by its contributors and licensed under CC BY-SA 4.0. Fathomly has changed the layout, removed citation markers, navigation and maintenance notices, and adjusted punctuation. This adapted version is shared under the same license. For references, see the original article.

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