BLOC-1 subunit 6
Protein found in humans
BLOC-1 subunit 6 (also called Pallidin) is a protein that in humans is encoded by the BLOC1S6 gene (previously PLDN). This protein is part of Biogenesis of lysosome-related organelles complex 1 (BLOC-1), which is a protein complex which is involved in the biogenesis of the lysosome-related organelles (LROs) like dense granules and melanosomes.
01Function
The protein encoded by this gene may play a role in intracellular vesicle trafficking. It interacts with Syntaxin 13 which mediates intracellular membrane fusion. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
02Interactions
Sources and credits
This article is adapted from the Wikipedia article “BLOC-1 subunit 6”, written by its contributors and licensed under CC BY-SA 4.0. Fathomly has changed the layout, removed citation markers, navigation and maintenance notices, and adjusted punctuation. This adapted version is shared under the same license. For references, see the original article.
Images, from Wikimedia Commons:
- Ideogram human chromosome 15.svg by National Center for Biotechnology Information, U.S. National Library of Medicine, Public domain
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