PHF1
Protein-coding gene in the species Homo sapiens
01Function
This gene encodes a protein with significant sequence similarity to Drosophila Polycomblike. The encoded protein contains a zinc finger-like PHD (plant homeodomain) finger which is distinct from other classes of zinc finger motifs and which shows the typical Cys4-His-Cys3 arrangement. PHD finger genes are thought to belong to a diverse group of transcriptional regulators possibly affecting eukaryotic gene expression by influencing chromatin structure. Two transcript variants have been found for this gene.
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Images, from Wikimedia Commons:
- Ideogram human chromosome 6.svg by National Center for Biotechnology Information, U.S. National Library of Medicine, Public domain
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