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NUTF2

Protein-coding gene in the species Homo sapiens

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Nuclear transport factor 2 is a protein that in humans is encoded by the NUTF2 gene.

01Function

The protein encoded by this gene is a cytosolic factor that facilitates protein transport into the nucleus. It interacts with the nuclear pore complex glycoprotein p62. This encoded protein acts at a relative late stage of nuclear protein import, subsequent to the initial docking of nuclear import ligand at the nuclear envelope. It is thought to be part of a multicomponent system of cytosolic factors that assemble at the pore complex during nuclear import.

02Interactions

NUTF2 has been shown to interact with Nucleoporin 62 and RAN.

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Sources and credits

This article is adapted from the Wikipedia article NUTF2, written by its contributors and licensed under CC BY-SA 4.0. Fathomly has changed the layout, removed citation markers, navigation and maintenance notices, and adjusted punctuation. This adapted version is shared under the same license. For references, see the original article.

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