Musk
Class of aromatic substances used in perfumes

Musk is a class of aromatic substances commonly used as base notes in perfumery. They include glandular secretions from animals such as the musk deer, numerous plants emitting similar fragrances, and artificial substances with similar odors. Musk was a name originally given to a substance with a strong odor obtained from a gland of the musk deer. The substance has been used as a popular perfume fixative since ancient times and is one of the most expensive animal products in the world. The name originates from the Late Greek μόσχος 'moskhos', from Persian mushk, in turn from Sanskrit मुष्क muṣka (lit. 'testicle') derived from Proto-Indo-European noun múh₂s meaning "mouse". The deer gland was thought to resemble a scrotum. The term is applied to various plants and animals of similar smell (e.g., muskox) and has come to encompass a wide variety of aromatic substances with similar odors, despite their often differing chemical structures and molecular shapes.
Natural musk was used extensively in perfumery until the late 19th century when economic and ethical motives led to the adoption of synthetic musk, which is now used almost exclusively. The organic compound primarily responsible for the characteristic odor of musk is muscone. There are several ways of preparing the commercial musk, and the best method is to dry the pod by sunning and airing immediately after it is taken from the animal. Natural musk is usually packed in hermetically-sealed vessels and wooden boxes lined with tin foil because of its powerful diffusion of odor.
Modern use of natural musk pods occurs in traditional Chinese medicine which, save for specially exempt drugs, uses a synthetic version of undisclosed composition created in 1994. The process was given State Science and Technology Progress Award First Class in 2015.
01Synthesis
Since obtaining the deer musk requires killing the endangered animal, nearly all musk fragrance used in perfumery today is synthetic, sometimes called "white musk". They can be divided into three major classes: aromatic nitro musks, polycyclic musk compounds, and macrocyclic musk compounds. The first two groups have broad uses in industry ranging from cosmetics to detergents. The detection of the first two chemical groups in human and environmental samples as well as their carcinogenic properties initiated a public debate on the use of these compounds and a ban or reduction of their use in many regions of the world. Macrocyclic musk compounds are expected to replace them since these compounds appear to be safer.


02Fragrance and flavorant
Musk is often associated with religious significance. It appears in Buddhist, Hindu and Sufi texts and poetry. Kabir uses a musk deer parable that describes a deer smelling a beautiful scent that it searches for everywhere, unaware that the fragrance comes from its own navel. This parable symbolizes people's mistaken search for God or truth outside when it already resides within. In Islam, musk is considered to be the most fragrant of the scents. It was widely used by the Islamic prophet Muhammad and his companions. Alexander the Great is also said to have perspired the odor of musk. Popular scents in Arab Muslim tradition include jasmine, amber, musk and oud (agarwood).
Orchid paired with musk is a recurring scent combination associated with women's clothing and bedchambers in classical vernacular Chinese literature.
Musk has been used to attract wild animals, including in man-made perfume mixtures. For example, in 2018 Indian authorities used the perfume Obsession by Calvin Klein to attract and thus trap a wild tiger that had attacked and killed more than a dozen humans.
Musk sticks, which are artificially flavoured with a substance that is reminiscent of musk perfume, are a popular confection in Australia.

Sources and credits
This article is adapted from the Wikipedia article “Musk”, written by its contributors and licensed under CC BY-SA 4.0. Fathomly has changed the layout, removed citation markers, navigation and maintenance notices, and adjusted punctuation. This adapted version is shared under the same license. For references, see the original article.
Images, from Wikimedia Commons:
- Naturalists Library - Mammalia - Volume III - The Thibetian Musk.jpg by James Hope Stewart, Public domain
- Primary Form of Musk.jpg by 乌拉跨氪, CC BY-SA 3.0
- Ondatra zibethicus FWS.jpg by David Menke, Public domain
- Galaxolide.svg by Sjschen, CC BY 3.0
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