Methorphan
Group of stereoisomers
Methorphan is an opioid drug that occurs in two isomeric forms, each with differing pharmacology and effects:
- Dextromethorphan , An over-the-counter cough suppressant, as well as dissociative hallucinogen.
- Levomethorphan , A potent opioid analgesic that was never clinically developed; a prodrug of the powerful opioid agonist analgesic levorphanol (Levo-Dromoran).
Racemethorphan is the racemic mixture of both of these stereoisomers. It is listed under the Single Convention on Narcotic Drugs 1961 and is therefore listed in the United States as a Controlled Substance, specifically as a Narcotic in Schedule II with an ACSCN of 9732 and an annual aggregate manufacturing quota of 3 grams in 2014. The salts in use are the hydrobromide (free base conversion ratio 0.770) and the tartrate (0.644).
Sources and credits
This article is adapted from the Wikipedia article “Methorphan”, written by its contributors and licensed under CC BY-SA 4.0. Fathomly has changed the layout, removed citation markers, navigation and maintenance notices, and adjusted punctuation. This adapted version is shared under the same license. For references, see the original article.
Images, from Wikimedia Commons:
- Levomethorphan.svg by Fvasconcellos, Public domain
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