MED25
Protein-coding gene in the species Homo sapiens
Mediator of RNA polymerase II transcription subunit 25 is an enzyme that in humans is encoded by the MED25 gene.
01Intellectual developmental disorder
A homozygous variant in the MED25 gene, leading to an arginine to trypsin substitution, was identified in seven individuals with impaired intellectual development and characteristic facial features. The genetic variant segregated with the disorder and was not found in control populations. This putative homozygous variant arose 218 years ago in this Brazilian family.
02Interactions
Sources and credits
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Images, from Wikimedia Commons:
- Ideogram human chromosome 19.svg by National Center for Biotechnology Information, U.S. National Library of Medicine, Public domain
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