LMX1B
Protein-coding gene in the species Homo sapiens
LIM homeobox transcription factor 1-beta, also known as LMX1B, is a protein which in humans is encoded by the LMX1B gene.
01Function
LMX1B is a LIM homeobox transcription factor which plays a central role in dorso-ventral patterning of the vertebrate limb.
02Clinical significance
Loss-of-function mutations in the LMX1B gene are associated with Nail-patella syndrome.
Sources and credits
This article is adapted from the Wikipedia article “LMX1B”, written by its contributors and licensed under CC BY-SA 4.0. Fathomly has changed the layout, removed citation markers, navigation and maintenance notices, and adjusted punctuation. This adapted version is shared under the same license. For references, see the original article.
Images, from Wikimedia Commons:
- Ideogram human chromosome 9.svg by National Center for Biotechnology Information, U.S. National Library of Medicine, Public domain
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