KIF22
Protein-coding gene in the species Homo sapiens
Kinesin-like protein KIF22 is a protein that in humans is encoded by the KIF22 gene.
The protein encoded by this gene is a member of kinesin-like protein family. This family of proteins are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. The C-terminal half of this protein has been shown to bind DNA. Studies with the Xenopus homolog suggests an essential role in metaphase chromosome alignment and maintenance.
01Interactions
02Clinical relevance
Mutations in this gene have been shown to cause developmental disorders such as Spondyloepimetaphyseal dysplasia with joint laxity.
Sources and credits
This article is adapted from the Wikipedia article “KIF22”, written by its contributors and licensed under CC BY-SA 4.0. Fathomly has changed the layout, removed citation markers, navigation and maintenance notices, and adjusted punctuation. This adapted version is shared under the same license. For references, see the original article.
Images, from Wikimedia Commons:
- Protein KIF22 PDB 2EDU.png by Pleiotrope, Public domain
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