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Isotryptamine

Chemical compound

Wikipedia contributorsAdapted for Fathomly · View authors
1 min read
Source updated February 15, 2026
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Isotryptamine, also known as 2-(1-indolyl)ethylamine, is a chemical compound and positional isomer of tryptamine (2-(3-indolyl)ethylamine). A variety of isotryptamine derivatives, or substituted isotryptamines, have been studied and described.

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This article is adapted from the Wikipedia article “Isotryptamine”, written by its contributors and licensed under CC BY-SA 4.0. Fathomly has changed the layout, removed citation markers, navigation and maintenance notices, and adjusted punctuation. This adapted version is shared under the same license. For references, see the original article.

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Related topics

Substituted isotryptamine

Substituted isotryptamines, or simply isotryptamines, also known as 2-ethylamines, are a group of indoles closely related to the tryptamines but with the ethylamine side chain located at the 1 position of the indole ring system rather than at the 3 position as in tryptamines. Hence, they are positional isomers of tryptamines.

Substituted tryptamine

Substituted tryptamines, or simply tryptamines, also known as serotonin analogues, are organic compounds which may be thought of as being derived from tryptamine itself. The molecular structures of all tryptamines contain an indole ring system, joined to an amino (NH2) group via an ethyl (−CH2-CH2−) sidechain.