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Indorenate

Chemical compound

Wikipedia contributorsAdapted for Fathomly · View authors
1 min read
Source updated May 11, 2026
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Indorenate (developmental code name TR-3369), also known as β-methoxycarbonyl-5-methoxytryptamine, is a tryptamine derivative which acts as an agonist at the 5-HT1A, 5-HT1B and 5-HT2C serotonin receptors. It has anxiolytic, antihypertensive and anorectic effects, predominantly through action at 5-HT1A, but with some contribution from the 5-HT1B and 5-HT2C subtypes, and possibly some other non-serotonergic targets also. In addition to the preceding serotonin receptors, indorenate may also act as an agonist of the serotonin 5-HT2A receptor.

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This article is adapted from the Wikipedia article “Indorenate”, written by its contributors and licensed under CC BY-SA 4.0. Fathomly has changed the layout, removed citation markers, navigation and maintenance notices, and adjusted punctuation. This adapted version is shared under the same license. For references, see the original article.

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Substituted tryptamine

Substituted tryptamines, or simply tryptamines, also known as serotonin analogues, are organic compounds which may be thought of as being derived from tryptamine itself. The molecular structures of all tryptamines contain an indole ring system, joined to an amino (NH2) group via an ethyl (−CH2-CH2−) sidechain.

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