GRIN2D
Protein-coding gene in the species Homo sapiens
Glutamate [NMDA] receptor subunit epsilon-4 is a protein that in humans is encoded by the GRIN2D gene.
01Function
N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D).
02Interactions
GRIN2D has been shown to interact with Interleukin 16.
Sources and credits
This article is adapted from the Wikipedia article “GRIN2D”, written by its contributors and licensed under CC BY-SA 4.0. Fathomly has changed the layout, removed citation markers, navigation and maintenance notices, and adjusted punctuation. This adapted version is shared under the same license. For references, see the original article.
Images, from Wikimedia Commons:
- Glycine and glutamate bound Human GluN1a-GluN2D NMDA receptor - Glutamate receptor ionotropic, NMDA 2D - 8E96.png by Chou, T.-H., Furukawa, H., CC0
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