Protein wntless homolog
Protein-coding gene in the species Homo sapiens
Protein wntless homolog, commonly known as Wntless, is encoded in humans by the WLS gene. Wntless is a receptor for Wnt proteins in Wnt-secreting cells.
Wntless was shown to be a cargo for the retromer complex. It has been found essential for hair follicle induction.
A homozygous missense mutation in the WLS gene was identified in Zaki syndrome.
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Images, from Wikimedia Commons:
- Ideogram human chromosome 1.svg by National Center for Biotechnology Information, U.S. National Library of Medicine, Public domain
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