FOXO6
Protein-coding gene in humans
Forkhead box O6 is a protein that in humans is encoded by the FOXO6 gene.
FoxO6 is expressed in the liver, skeletal muscle, and the hippocampus of the brain. In the liver, FoxO6 normally promotes gluconeogenesis in the fasted state, but insulin blocks Fox06 after feeding. In a condition of insulin resistance, insulin fails to block FoxO6, resulting in continued gluconeogenesis even after feeding.
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This article is adapted from the Wikipedia article “FOXO6”, written by its contributors and licensed under CC BY-SA 4.0. Fathomly has changed the layout, removed citation markers, navigation and maintenance notices, and adjusted punctuation. This adapted version is shared under the same license. For references, see the original article.
Images, from Wikimedia Commons:
- Ideogram human chromosome 1.svg by National Center for Biotechnology Information, U.S. National Library of Medicine, Public domain
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