EIF2A
Protein-coding gene in the species Homo sapiens
Eukaryotic translation initiation factor 2A (eIF2A) is a protein that in humans is encoded by the EIF2A gene. The eIF2A protein is not to be confused with eIF2α, a subunit of the heterotrimeric eIF2 complex. Instead, eIF2A functions by a separate mechanism in eukaryotic translation.
01Function
eIF2A is a 65 kDa protein that catalyzes the formation of puromycin-sensitive 80S preinitiation complexes (Zoll et al., 2002).[supplied by OMIM] It may be important for translation initiation mediated by the HCV IRES under stress conditions, but this result has been debated.
Sources and credits
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Images, from Wikimedia Commons:
- Ideogram human chromosome 3.svg by National Center for Biotechnology Information, U.S. National Library of Medicine, Public domain
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