Dimetofrine
Chemical compound
Dimetofrine (INNTooltip International Nonproprietary Name), also known as dimethophrine or dimetophrine and sold under the brand names Dovida, Pressamina, and Superten, is a medication described as a sympathomimetic, vasoconstrictor, and cardiac stimulant. It is said to be similarly or less effective than midodrine in the treatment of orthostatic hypotension and shows substantially lower potency.
The drug is a selective α1-adrenergic receptor agonist but is also said to have β-adrenergic receptor agonist activity. It is a substituted phenethylamine and is also known as 3,5-dimethoxy-4,β-dihydroxy-N-methylphenethylamine. Its chemical structure is similar to that of desglymidodrine (2,5-dimethoxy-β-hydroxyphenethylamine), the active metabolite of midodrine.
Dimetofrine remained marketed only in Italy in 2000.
Sources and credits
This article is adapted from the Wikipedia article “Dimetofrine”, written by its contributors and licensed under CC BY-SA 4.0. Fathomly has changed the layout, removed citation markers, navigation and maintenance notices, and adjusted punctuation. This adapted version is shared under the same license. For references, see the original article.
Images, from Wikimedia Commons:
- Dimetofrine.svg by AlyInWikiWonderland, CC0
Fathomly is not affiliated with or endorsed by the Wikimedia Foundation. Spotted a problem? Tell us.
