DYNLT1
Protein-coding gene in the species Homo sapiens
Dynein light chain Tctex-type 1 is a protein that in humans is encoded by the DYNLT1 gene.
Cytoplasmic dynein is the major motor protein complex responsible for minus-end, microtubule-based motile processes. Each dynein complex consists of 2 heavy chains that have ATPase and motor activities, plus a group of accessory polypeptides. TCTEX1 is a dynein light chain involved in cargo binding (Chuang et al., 2005).[supplied by OMIM]
In cancer patients, DYNLT1 expression has been linked to both higher and lower survival rates, depending on cancer type.
Sources and credits
This article is adapted from the Wikipedia article “DYNLT1”, written by its contributors and licensed under CC BY-SA 4.0. Fathomly has changed the layout, removed citation markers, navigation and maintenance notices, and adjusted punctuation. This adapted version is shared under the same license. For references, see the original article.
Images, from Wikimedia Commons:
- Ideogram human chromosome 6.svg by National Center for Biotechnology Information, U.S. National Library of Medicine, Public domain
Fathomly is not affiliated with or endorsed by the Wikimedia Foundation. Spotted a problem? Tell us.