Reference articles on history, science, culture and more
Encyclopedia

Complement component 1s

Protein found in humans

Image credit is listed at the end of this article.

Complement component 1s (EC 3.4.21.42, C1 esterase, activated complement C1s, complement C overbar 1r, C1s) is a protein involved in the complement system. C1s is part of the C1 complex. In humans, it is encoded by the C1S gene.

C1s cleaves C4 and C2, which eventually leads to the production of the classical pathway C3-convertase.

Classical pathway. (Some labels are in Polish.)
Classical pathway. (Some labels are in Polish.)
Watch videos about Complement component 1sExplainers and documentaries on YouTube (opens in a new tab)

Sources and credits

This article is adapted from the Wikipedia article Complement component 1s, written by its contributors and licensed under CC BY-SA 4.0. Fathomly has changed the layout, removed citation markers, navigation and maintenance notices, and adjusted punctuation. This adapted version is shared under the same license. For references, see the original article.

Images, from Wikimedia Commons:

Fathomly is not affiliated with or endorsed by the Wikimedia Foundation. Spotted a problem? Tell us.