CNTRL
Protein-coding gene in the species Homo sapiens
Centriolin is a protein that in humans is encoded by the CNTRL gene. It was previously known as CEP110.
This gene encodes a centrosomal protein required for the centrosome to function as a microtubule organizing center. The gene product is also associated with centrosome maturation. One version of stem cell myeloproliferative disorder is the result of a reciprocal translocation between chromosomes 8 and 9, with the breakpoint associated with fibroblast growth factor receptor 1 and centriolin.
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This article is adapted from the Wikipedia article “CNTRL”, written by its contributors and licensed under CC BY-SA 4.0. Fathomly has changed the layout, removed citation markers, navigation and maintenance notices, and adjusted punctuation. This adapted version is shared under the same license. For references, see the original article.
Images, from Wikimedia Commons:
- Ideogram human chromosome 9.svg by National Center for Biotechnology Information, U.S. National Library of Medicine, Public domain
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