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CD7

Mammalian protein found in humans

Wikipedia contributorsAdapted for Fathomly · View authors
1 min read
Source updated July 19, 2025
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CD7 (Cluster of Differentiation 7) is a protein that in humans is encoded by the CD7 gene.

01Function

This gene encodes a transmembrane protein which is a member of the immunoglobulin superfamily. This protein is found on thymocytes and mature T cells. It plays an essential role in T-cell interactions and also in T-cell/B-cell interaction during early lymphoid development.

02Interactions

CD7 has been shown to interact with PIK3R1.

03Clinical significance

CD7 can be aberrantly expressed in refractory anaemia with excess blasts (RAEB) and may confer a worse prognosis. Also, a lack of CD7 expression could insinuate mycosis fungoides (MF) or Sezary syndrome (SS).

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Sources and credits

This article is adapted from the Wikipedia article “CD7”, written by its contributors and licensed under CC BY-SA 4.0. Fathomly has changed the layout, removed citation markers, navigation and maintenance notices, and adjusted punctuation. This adapted version is shared under the same license. For references, see the original article.

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