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CACYBP

Protein-coding gene in humans

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Calcyclin-binding protein is a protein that in humans is encoded by the CACYBP gene.

The protein encoded by this gene is a calcyclin binding protein. It may be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin-mediated degradation of beta-catenin. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.

01Protein interactions

CACYBP has been shown to interact with SKP1A and SIAH1.

The CacyBP/SIP complex instead, is known to be a part of stress respons, since it interacts with chaperone HSP90.

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Sources and credits

This article is adapted from the Wikipedia article CACYBP, written by its contributors and licensed under CC BY-SA 4.0. Fathomly has changed the layout, removed citation markers, navigation and maintenance notices, and adjusted punctuation. This adapted version is shared under the same license. For references, see the original article.

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