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Bruceolide

Chemical compound

Wikipedia contributorsAdapted for Fathomly · View authors
1 min read
Source updated August 12, 2026
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Bruceolide is a quassinoid that has been isolated from Bischofia javanica. Synthetic derivatives have shown in vitro antimalarial activity.

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This article is adapted from the Wikipedia article “Bruceolide”, written by its contributors and licensed under CC BY-SA 4.0. Fathomly has changed the layout, removed citation markers, navigation and maintenance notices, and adjusted punctuation. This adapted version is shared under the same license. For references, see the original article.

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Related topics

Quassinoid

Quassinoids are degraded triterpene lactones of the Simaroubaceae plant family grouped into C-18, C-19, C-20, C-22 and C-25 types. The prototypical member of the group, quassin, was first described in the 19th century from plants of the genus Quassia from which it gets its name.

Bischofia javanica

Bischofia javanica, or bishop wood, is a plant species of the family Phyllanthaceae. It and the related Bischofia polycarpa are the only two members of genus Bischofia and tribe Bischofieae.

Antimalarial medication

Antimalarial medications or simply antimalarials are a type of antiparasitic chemical agent, often naturally derived, that can be used to treat or to prevent malaria, in the latter case, most often aiming at two susceptible target groups, young children and pregnant women. While many treatments, including for severe malaria, continue to depend on therapies deriving historically from the injectable drugs quinine and artesunate, the development of drug resistance in the parasite has necessitated the development new antimalarial therapies.