Apolipoprotein A-II
Protein found in humans
| ApoA-II | |
|---|---|
| structures of apolipoprotein a-ii and a lipid surrogate complex provide insights into apolipoprotein-lipid interactions | |
| Identifiers | |
| Symbol | ApoA-II |
| Pfam | PF04711 |
| InterPro | IPR006801 |
| SCOP2 | 1l6k / SCOPe / SUPFAM |
Apolipoprotein A-II is a protein that in humans is encoded by the APOA2 gene. It is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. ApoA-II regulates many steps in HDL metabolism, and its role in coronary heart disease is unclear. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia.
01Interactions
ApoA-II has been shown to interact with phospholipid transfer protein.
02Interactive pathway map
Click on genes, proteins and metabolites below to link to respective articles.
Sources and credits
This article is adapted from the Wikipedia article “Apolipoprotein A-II”, written by its contributors and licensed under CC BY-SA 4.0. Fathomly has changed the layout, removed citation markers, navigation and maintenance notices, and adjusted punctuation. This adapted version is shared under the same license. For references, see the original article.
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