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AJUBA

Protein-coding gene in the species Homo sapiens

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LIM domain-containing protein ajuba (or ajuba for short) is a protein that in humans is encoded by the AJUBA gene (previously JUB).

01Function

Ajuba contributes to cell fate determination and regulates cell proliferation and differentiation. It plays an important role in the regulation of the kinase activity of AURKA/Aurora-A for mitotic commitment.

02Interactions

Ajuba has been shown to interact with Stratifin and SLC1A2.

03Name

The protein was first discovered in mice, and named "ajuba" after the Urdu word for "curiosity".

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Sources and credits

This article is adapted from the Wikipedia article AJUBA, written by its contributors and licensed under CC BY-SA 4.0. Fathomly has changed the layout, removed citation markers, navigation and maintenance notices, and adjusted punctuation. This adapted version is shared under the same license. For references, see the original article.

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